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Article

[Driver Mutations in Acute Myeloid Leukemia with Inversion of Chromosome 16].

Molekuliarnaia biologiia - 1 Jan 2000

Ghukasyan L G, Krasnov G S, Muravenko O V, Ikonnikova A Y, Yurasov R A, Baidun L V, Ibragimova S Z, Nasedkina T V

Abstract excerpt

Certain subtypes of acute myeloid leukemia occur as a result of the cooperation of several events these are, the formation of fusion genes as a result of chromosomal rearrangements, which leads to the disruption of cell differentiation, and the emergence of mutations that enhance cellular proliferation by activating intracellular signaling pathways. High-throughput sequencing methods reveal characteristic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32492002
DOI: 10.31857/S002689842003015510.31857/S0026898420030076

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