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Article

[Genetic abnormalities in AML].

[Rinsho ketsueki] The Japanese journal of clinical hematology - 1 Jan 2019

Nakajima Hideaki

Abstract excerpt

Genetic abnormalities of acute myeloid leukemia (AML) include chromosomal translocations and gene mutations. Commonly observed chromosomal abnormalities in AML are t (8;21), t (15;17), inv (16), and 11q23-related translocations. These aberrations produce RUNX1-RUNX1T1, PML-RARA, CBF-MYH11, and MLL-fusion genes, respectively, which promote leukemic stem cell formation by interfering with hematopoietic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Leukemia, Myeloid, Acute

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Source

Identifiers

PMID: 31281149
DOI: 10.11406/rinketsu.60.584

Genes

DNMT3A
FLT3
MYH11
NPM1
PML
RARA
RUNX1
RUNX1T1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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