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[Analysis of tyrosine kinases gene mutations in core binding factor related acute myeloid leukemia and its clinical significance].

Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi - 1 Oct 2011

Qiao Man, Li Wei-yang, Sun Ai-ning, Chen Su-ning, Liang Jian-ying, Ding Zi-xuan, Feng Yu-feng, Wu De-pei

Abstract excerpt

OBJECTIVE: To assess the prevalence of several tyrosine kinases (TKs) gene mutations including c-Kit, FLT3 and JAK2 V617F in core binding factor related acute myeloid leukemia (CBF-AML), and analyze their impact on clinical characteristics and prognosis. METHODS: Mutations of c-Kit, FLT3-ITD and FLT3-TKD were detected by genomic DNA PCR and sequencing, and JAK2 V617F mutation screening by allele-specific PCR in...

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PMID: 22339826

Genes

FLT3
JAK2

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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