Article
Parallel Evolution of Tobramycin Resistance across Species and Environments.
mBio - 26 May 2020
Scribner Michelle R, Santos-Lopez Alfonso, Marshall Christopher W, Deitrick Christopher, Cooper Vaughn S
Abstract excerpt
Different species exposed to a common stress may adapt by mutations in shared pathways or in unique systems, depending on how past environments have molded their genomes. Understanding how diverse bacterial pathogens evolve in response to an antimicrobial treatment is a pressing example of this problem, where discovery of molecular parallelism could lead to clinically useful predictions. Evolution experiments...
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