Article
Using experimental evolution to identify druggable targets that could inhibit the evolution of antimicrobial resistance.
The Journal of antibiotics - 1 Feb 2018
Mehta Heer H, Prater Amy G, Shamoo Yousif
Abstract excerpt
With multi-drug and pan-drug-resistant bacteria becoming increasingly common in hospitals, antibiotic resistance has threatened to return us to a pre-antibiotic era that would completely undermine modern medicine. There is an urgent need to develop new antibiotics and strategies to combat resistance that are substantially different from earlier drug discovery efforts. One such strategy that would complement...
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