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Article

stim2b Knockout Induces Hyperactivity and Susceptibility to Seizures in Zebrafish Larvae.

Cells - 21 May 2020

Wasilewska Iga, Gupta Rishikesh Kumar, Wojtaś Bartosz, Palchevska Oksana, Kuźnicki Jacek

Abstract excerpt

In neurons, stromal interaction molecule (STIM) proteins regulate store-operated Ca2+ entry (SOCE) and are involved in calcium signaling pathways. However, STIM activity in neurological diseases is unclear and should be clarified by studies that are performed in vivo rather than in cultured cells in vitro. The present study investigated the role of neuronal Stim2b protein in zebrafish. We generated stim2b...

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PMID: 32455839
DOI: 10.3390/cells9051285
PMCID: PMC7291033

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stim2b Knockout Induces Hyperactivity and Susceptibility to Seizures in Zebrafish Larvae.PMID 32455839Read ↗

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