Article
Common variants in LTBP3 gene contributed to the risk of hip osteoarthritis in Han Chinese population.
Bioscience reports - 26 Jun 2020
Zhao Tianyun, Zhao Junji, Ma Chi, Wei Jie, Wei Bo, Liu Jibin
Abstract excerpt
Osteoarthritis (OA) is a common chronic joint disease affected by environmental and genetic factors. The LTBP3 gene may be involved in the occurrence and development of OA by regulating TGF-β activity and the TGF-β signaling pathway. A total of 2780 study subjects, including 884 hip OA cases and 1896 controls, were recruited. Nine tag single-nucleotide polymorphisms (SNPs) located within the LTBP3 gene region...
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