Article
Correlation of growth differentiation factor-5 + 104T>C polymorphism with the risk of knee, hand, and hip osteoarthritis: a case-control study and meta-analysis based on 47 case-control studies.
Nucleosides, nucleotides & nucleic acids - 1 Jan 2024
Alijanpour Kamran, Dastgheib Seyed Alireza, Azizi Leila, Shiri Amirmasoud, Bahrami Mohammad, Aghasipour Maryam, Miri Somaye, Aghili Kazem, Dehghani-Manshadi Zinatalsadat, Neamatzadeh Hossein, Khajehnoori Sahel
Abstract excerpt
Osteoarthritis (OA) arises from a intricate interplay of genetic and environmental factors. Numerous studies have explored the link between the growth differentiation factor 5 (GDF-5) +104T>C polymorphism and OA risk, but the findings have been inconclusive. We carried out a case-control study with 704 OA cases and 418 healthy controls. Furthermore, we conducted a meta-analysis by thoroughly searching the...
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