Article
Association study of the functional variants of the GLIS3 gene with risk of knee osteoarthritis.
Clinical rheumatology - 1 Mar 2021
Zhang Jian-Luo, Zhang Cun-Li, Zhou Bai-Gang, Lei Bo-Yi, Zhang Bo, Yang Hong-Tao
Abstract excerpt
INTRODUCTION/OBJECTIVES: Osteoarthritis (OA) ranks the most common joint disorder and the leading cause of disability. Growing evidence has revealed that OA has a strong genetic background, except for aging and obesity. The aim of this study is to determine the associations between potential functional variants of the GLIS3 and GLIS3-AS1 gene and risk of knee OA among a Chinese population. METHODS: In this...
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