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Article

Common variants in GNL3 gene contributed the susceptibility of hand osteoarthritis in Han Chinese population.

Scientific reports - 27 Sept 2022

Wang Xi, Xiao Lin, Wang Zhiyuan, Zhi Liqiang, Li Qiang

Abstract excerpt

Osteoarthritis (OA) is one of the most popular degenerative joint diseases. The nucleolar GTP binding protein 3 (GNL3) gene encodes guanine nucleotide binding protein-like 3, which is related in cell proliferation, differentiation, and cell cycle regulation. Our study aimed to examine the contribution of GNL3 gene polymorphisms to the risk of hand OA and its related clinical features. A total of 3387 study...

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Identifiers

PMID: 36167888
DOI: 10.1038/s41598-022-20287-4
PMCID: PMC9515075

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