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Article

Common variants in the GNL3 contribute to the increasing risk of knee osteoarthritis in Han Chinese population.

Scientific reports - 25 Jun 2018

Liu Bo, Cheng Huiguang, Ma Wenlong, Gong Futai, Wang Xiangyang, Duan Ning, Dang Xiaoqian

Abstract excerpt

Osteoarthritis (OA) is a complex degenerative joint disorder, which is caused by both environmental and genetic factors. Previous studies have indicated that the GNL3 gene is associated with knee osteoarthritis (KOA) susceptibility in Europeans; however, the exact molecular mechanism is still unclear. In the present study, we investigated the potential genetic association of GNL3 with KOA in a two-stage sample of...

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Identifiers

PMID: 29942097
DOI: 10.1038/s41598-018-27971-4
PMCID: PMC6018215

Genes

GNL3
SPCS1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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