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Article

The role of the uncoupling protein 1 (UCP1) on the development of obesity and type 2 diabetes mellitus.

Arquivos brasileiros de endocrinologia e metabologia - 1 Jun 2012

Brondani Letícia de Almeida, Assmann Taís Silveira, Duarte Guilherme Coutinho Kullmann, Gross Jorge Luiz, Canani Luís Henrique, Crispim Daisy

Abstract excerpt

It is well established that genetic factors play an important role in the development of both type 2 diabetes mellitus (DM2) and obesity, and that genetically susceptible subjects can develop these metabolic diseases after being exposed to environmental risk factors. Therefore, great efforts have been made to identify genes associated with DM2 and/or obesity. Uncoupling protein 1 (UCP1) is mainly expressed in...

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Identifiers

PMID: 22790465
DOI: 10.1590/s0004-27302012000400001

Genes

UCP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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The role of the uncoupling protein 1 (UCP1) on the development of obesity and type 2 diabetes mellitus.PMID 22790465Read ↗

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Uncoupling proteins: functional characteristics and role in the pathogenesis of obesity and Type II diabetes.Semantic proximity Read ↗

The polymorphisms of UCP2 and UCP3 genes associated with fat metabolism, obesity and diabetes.Semantic proximity Read ↗

Association between UCP polymorphisms and adipokines with obesity in Mexican adolescents.Semantic proximity Read ↗

Mitochondrial uncoupling protein 2 (UCP2) gene polymorphisms are associated with childhood obesity and related metabolic disorders.Semantic proximity Read ↗

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Genetic Variance in<i>Uncoupling Protein 2</i>in Relation to Obesity, Type 2 Diabetes, and Related Metabolic Traits: Focus on the Functional −866G>A Promoter Variant (rs659366)Semantic proximity Read ↗

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