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Article

Human uncoupling protein 2 and 3 genes are associated with obesity in Japanese.

Endocrine - 1 Jan 2000

Kosuge Kotoko, Soma Masayoshi, Nakayama Tomohiro, Aoi Noriko, Sato Mikano, Haketa Akira, Uwabo Jiro, Izumi Yoichi, Matsumoto Koichi

Abstract excerpt

Human uncoupling proteins (UCPs) are mitochondrial proteins that are involved in the control of energy metabolism and the pathophysiology of obesity. Although there have been several reports on the association between the UCP2/UCP3 locus and the obesity, there have been no haplotype-based case-control studies with gender-specific analysis. The aim of this study was to examine whether there is an association...

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Source

Identifiers

PMID: 18956255
DOI: 10.1007/s12020-008-9111-9

Genes

UCP2
UCP3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Human uncoupling protein 2 and 3 genes are associated with obesity in Japanese.PMID 18956255Read ↗

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Association of uncoupling protein (Ucp) gene polymorphisms with cardiometabolic diseases.Semantic proximity Read ↗

The common -55 C/T polymorphism in the promoter region of the uncoupling protein 3 gene reduces prevalence of obesity and elevates serum high-density lipoprotein cholesterol levels in the general Japanese population.Semantic proximity Read ↗

Association of the ins/del polymorphisms of uncoupling protein 2 (UCP2) with BMI in a Korean population.Semantic proximity Read ↗

Unleash the Association of Mitochondrial Uncoupling Protein (UCP2) Promoter Variant (G-866A; rs659366) with Obesity: Stepping from a Case-Control Study to a Meta-analysis.Semantic proximity Read ↗

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