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Article

Serum neurofilament light chain in FTLD: association with C9orf72, clinical phenotype, and prognosis.

Annals of clinical and translational neurology - 1 Jun 2020

Cajanus Antti, Katisko Kasper, Kontkanen Aleksi, Jääskeläinen Olli, Hartikainen Päivi, Haapasalo Annakaisa, Herukka Sanna-Kaisa, Vanninen Ritva, Solje Eino, Hall Anette, Remes Anne M

Abstract excerpt

OBJECTIVE: The aim of the present study was to compare the levels of serum neurofilament light chain (sNfL) in frontotemporal lobar degeneration (FTLD) patients of different clinical subtypes (bvFTD, PPA, and FTLD-MND) and with or without the C9orf72 repeat expansion, and to correlate sNfL levels to disease progression, assessed by the brain atrophy rate and survival time. METHODS: The sNfL levels were determined...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32441885
DOI: 10.1002/acn3.51041
PMCID: PMC7318100

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