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Neurofilament light chain: a biomarker for genetic frontotemporal dementia

1 Jul 2016

Abstract excerpt

OBJECTIVE: To evaluate cerebrospinal fluid (CSF) and serum neurofilament light chain (NfL) levels in genetic frontotemporal dementia (FTD) as a potential biomarker in the presymptomatic stage and during the conversion into the symptomatic stage. Additionally, to correlate NfL levels to clinical and neuroimaging parameters. METHODS: In this multicenter case-control study, we investigated CSF NfL in 174 subjects...

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PMID: 27606344
DOI: 10.1002/acn3.325

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