Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Comprehensive cross-sectional and longitudinal comparisons of plasma glial fibrillary acidic protein and neurofilament light across FTD spectrum disorders

12 Mar 2025

Abstract excerpt

BACKGROUND: Therapeutic development for frontotemporal dementia (FTD) is hindered by the lack of biomarkers that inform susceptibility/risk, prognosis, and the underlying causative pathology. Blood glial fibrillary acidic protein (GFAP) has garnered attention as a FTD biomarker. However, investigations of GFAP in FTD have been hampered by symptomatic and histopathologic heterogeneity and small cohort sizes...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alzheimer's disease research and treatments
Share to Amyotrophic Lateral Sclerosis Research
Share to Dementia and Cognitive Impairment Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 40075459
DOI: 10.1186/s13024-025-00821-4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Comprehensive cross-sectional and longitudinal comparisons of plasma glial fibrillary acidic protein and neurofilament light across FTD spectrum disordersPMID 40075459Read ↗

Comprehensive cross-sectional and longitudinal analyses of plasma neurofilament light across FTD spectrum disordersSemantic proximity Read ↗

Plasma glial fibrillary acidic protein and neurofilament light chain in behavioural variant frontotemporal dementia and primary psychiatric disordersSemantic proximity Read ↗

<i>APOE</i>and<i>TREM2</i>variants differentially influence glial fibrillary acidic protein and neurofilament light in plasma of UK Biobank participantsSemantic proximity Read ↗

Plasma Neurofilament Light Chain and Clinical Diagnosis in Frontotemporal Dementia SyndromesSemantic proximity Read ↗

Plasma glial fibrillary acidic protein is raised in progranulin-associated frontotemporal dementia.Semantic proximity Read ↗

NfL reliability across laboratories, stage-dependent diagnostic performance and matrix comparability in genetic FTD: a large GENFI study.Semantic proximity Read ↗

Neurofilament light chain: a biomarker for genetic frontotemporal dementiaSemantic proximity Read ↗

Plasma neurofilament light in behavioural variant frontotemporal dementia compared to mood and psychotic disordersSemantic proximity Read ↗

Stratifying the Presymptomatic Phase of Genetic Frontotemporal Dementia by Serum NfL and pNfH : A Longitudinal Multicentre StudySemantic proximity Read ↗

Blood-Based Biomarkers in Frontotemporal Dementia: A Narrative Review.Semantic proximity Read ↗

Clinicopathological and prognostic correlations of plasma biomarkers in neurodegenerative diseasesSemantic proximity Read ↗

Serum neurofilament light levels correlate with severity measures and neurodegeneration markers in autosomal dominant Alzheimer’s diseaseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.