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Somatic mutations of triple-negative breast cancer: a comparison between Black and White women.

Breast cancer research and treatment - 1 Jul 2020

Omilian Angela R, Wei Lei, Hong Chi-Chen, Bandera Elisa V, Liu Song, Khoury Thaer, Ambrosone Christine B, Yao Song

Abstract excerpt

PURPOSE: Understanding the contribution of tumor genome biology to racial disparities of triple-negative breast cancer (TNBC) is important for narrowing the cancer mortality gap between Black and White women. METHODS: We evaluated tumor somatic mutations using targeted sequencing of a customized panel of 151 genes and 15 copy number variations (CNVs) within a population of 133 TNBC patients, including 71 Black...

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Identifiers

PMID: 32441016
DOI: 10.1007/s10549-020-05693-4
PMCID: PMC7313393

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