Article

Cis-Compound Mutations are Prevalent in Triple Negative Breast Cancer and Can Drive Tumor Progression

2016-11-05

Abstract excerpt

About 16% of breast cancers fall into a clinically aggressive category designated triple negative (TNBC) due to a lack of ERBB2, estrogen receptor and progesterone receptor expression 1-3 . The mutational spectrum of TNBC has been characterized as part of The Cancer Genome Atlas (TCGA) 4 ; however, snapshots of primary tumors cannot reveal the mechanisms by which TNBCs progress and spread. To address this limita...

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Literature Corpus work: cfe2fa3f-14e3-5afd-82c2-730c509a5854
DOI: 10.1101/085316

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