Article
Somatic gene mutation analysis of triple negative breast cancers.
Breast (Edinburgh, Scotland) - 1 Oct 2016
Dillon J L, Mockus S M, Ananda G, Spotlow V, Wells W A, Tsongalis G J, Marotti J D
Abstract excerpt
OBJECTIVES: The aims of this study were to analyze triple negative breast cancer (TNBC) using an expanded next generation sequencing (NGS) assay, assess the clinical relevance using a recently described database, and correlate tumor morphology with detected genetic alterations. METHODS: DNA was isolated from twenty primary TNBCs and genes of interest were enriched and sequenced with hybrid capture, followed by...
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