Article
Germline pathogenic variants in Mexican patients with hereditary triple-negative breast cancer.
Salud publica de Mexico - 25 Feb 2022
Chavarri-Guerra Yanin, Villarreal-Garza Cynthia, Ferrigno Ana S, Mohar Alejandro, Aguilar Dione, Alvarez-Gomez Rosa M, Gallardo-Alvarado Lenny, Del Toro-Valero Azucena, Quintero-Beulo Gregorio, Gutierrez-Delgado Francisco, Rodriguez-Olivares José Luis, Ochoa-Chavez Maria Fernanda, Gutierrez-Seymour Gubidxa, Castillo Danielle, Herzog Josef, Weitzel Jeffrey N
Abstract excerpt
OBJECTIVE: Describe the prevalence of breast cancer (BC)- associated germline pathogenic variants (PVs) among Mexican patients with triple-negative BC (TNBC). MATERIALS AND METHODS: The spectrum of PVs identified among patients with TNBC who were enrolled in a prospective registry and underwent genetic testing was analyzed. RESULTS: Of 387 patients with invasive TNBC and a median age at diagnosis of 39 years...
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