Article
The Association of ARMC5 with the Renin-Angiotensin-Aldosterone System, Blood Pressure, and Glycemia in African Americans.
The Journal of clinical endocrinology and metabolism - 1 Aug 2020
Joseph Joshua J, Zhou Xiaofei, Zilbermint Mihail, Stratakis Constantine A, Faucz Fabio R, Lodish Maya B, Berthon Annabel, Wilson James G, Hsueh Willa A, Golden Sherita H, Lin Shili
Abstract excerpt
CONTEXT: Armadillo repeat containing 5 (ARMC5) on chromosome 16 is an adrenal gland tumor suppressor gene associated with primary aldosteronism, especially among African Americans (AAs). We examined the association of ARMC5 variants with aldosterone, plasma renin activity (PRA), blood pressure, glucose, and glycosylated hemoglobin A1c (HbA1c) in community-dwelling AAs. METHODS: The Jackson Heart Study is a...
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