Primary Aldosteronism and ARMC5 Variants.

doi:10.1210/jc.2014-4167

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Article

Primary Aldosteronism and ARMC5 Variants.

The Journal of clinical endocrinology and metabolism - 1 Jun 2015

Zilbermint Mihail, Xekouki Paraskevi, Faucz Fabio R, Berthon Annabel, Gkourogianni Alexandra, Schernthaner-Reiter Marie Helene, Batsis Maria, Sinaii Ninet, Quezado Martha M, Merino Maria, Hodes Aaron, Abraham Smita B, Libé Rossella, Assié Guillaume, Espiard Stéphanie, Drougat Ludivine, Ragazzon Bruno, Davis Adam, Gebreab Samson Y, Neff Ryan, Kebebew Electron, Bertherat Jérôme, Lodish Maya B, Stratakis Constantine A

Abstract excerpt

CONTEXT: Primary aldosteronism is one of the leading causes of secondary hypertension, causing significant morbidity and mortality. A number of genetic defects have recently been identified in primary aldosteronism, whereas we identified mutations in ARMC5, a tumor-suppressor gene, in cortisol-producing primary macronodular adrenal hyperplasia. OBJECTIVE: We investigated a cohort of 56 patients who were referred...

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Identifiers

PMID: 25822102
DOI: 10.1210/jc.2014-4167
PMCID: PMC4454793

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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