Article
Interaction of human immunodeficiency virus-1 and human immunodeficiency virus-2 capsid amino acid variants with human tripartite motif 5α protein SPRY domain and its association with pathogenesis.
Indian journal of medical microbiology - 1 Jan 2000
Ramalingam Veena Vadhini, Subramanian Suganya, Fletcher G John, Rupali Priscilla, Varghese George, Pulimood Susanne, Jeyaseelan Lakshmanan, Nandagopal Balaji, Sridharan Gopalan, Kannangai Rajesh
Abstract excerpt
Purpose: The sequence variation of human immunodeficiency virus (HIV) capsid region may influence and alter the susceptibility to human tripartite motif 5α protein (huTRIM5α). Materials and Methods: Molecular docking was carried out with huTRIM5α SPRY domain by the use of ClusPro and Hex docking program for HIV-1 and HIV-2 capsid sequences. Results: The sequence analysis on HIV-1 and HIV-2 capsid gag gene...
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