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Article

Functional Characterization of Neurofilament Light Splicing and Misbalance in Zebrafish.

Cells - 16 May 2020

Demy Doris Lou, Campanari Maria Letizia, Munoz-Ruiz Raphael, Durham Heather D, Gentil Benoit J, Kabashi Edor

Abstract excerpt

Neurofilaments (NFs), a major cytoskeletal component of motor neurons, play a key role in the differentiation, establishment and maintenance of their morphology and mechanical strength. The de novo assembly of these neuronal intermediate filaments requires the presence of the neurofilament light subunit (NEFL), whose expression is reduced in motor neurons in amyotrophic lateral sclerosis (ALS). This study used...

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Identifiers

PMID: 32429483
DOI: 10.3390/cells9051238
PMCID: PMC7291018

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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