Article
Functions of the intermediate filament cytoskeleton in the eye lens.
The Journal of clinical investigation - 1 Jul 2009
Song Shuhua, Landsbury Andrew, Dahm Ralf, Liu Yizhi, Zhang Qingjiong, Quinlan Roy A
Abstract excerpt
Intermediate filaments (IFs) are a key component of the cytoskeleton in virtually all vertebrate cells, including those of the lens of the eye. IFs help integrate individual cells into their respective tissues. This Review focuses on the lens-specific IF proteins beaded filament structural proteins 1 and 2 (BFSP1 and BFSP2) and their role in lens physiology and disease. Evidence generated in studies in both mice...
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