Article
Neurofilaments and neurological disease.
BioEssays : news and reviews in molecular, cellular and developmental biology - 1 Apr 2003
Al-Chalabi Ammar, Miller Christopher C J
Abstract excerpt
Neurofilaments are one of the major components of the neuronal cytoskeleton and are responsible for maintaining the calibre of axons. They are modified by post-translational changes that are regulated in complex fashions including by the interaction with neighbouring glial cells. Neurofilament accumulations are seen in several neurological diseases and neurofilament mutations have now been associated with...
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