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Article

Effect of ethanol on Munc13-1 C1 in Membrane: A Molecular Dynamics Simulation Study.

Alcoholism, clinical and experimental research - 1 Jul 2020

You Youngki, Das Joydip

Abstract excerpt

BACKGROUND: EtOH has a significant effect on synaptic plasticity. Munc13-1 is an essential presynaptic active zone protein involved in priming the synaptic vesicle and releasing neurotransmitter in the brain. It is a peripheral membrane protein and binds to the activator, diacylglycerol (DAG)/phorbol ester at its membrane-targeting C1 domain. Our previous studies identified Glu-582 of C1 domain as the...

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Identifiers

PMID: 32424866
DOI: 10.1111/acer.14363
PMCID: PMC7572713

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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