Article
Knowledge-based analyses reveal new candidate genes associated with risk of hepatitis B virus related hepatocellular carcinoma.
BMC cancer - 11 May 2020
Jiang Deke, Deng Jiaen, Dong Changzheng, Ma Xiaopin, Xiao Qianyi, Zhou Bin, Yang Chou, Wei Lin, Conran Carly, Zheng S Lilly, Ng Irene Oi-Lin, Yu Long, Xu Jianfeng, Sham Pak C, Qi Xiaolong, Hou Jinlin, Ji Yuan, Cao Guangwen, Li Miaoxin
Abstract excerpt
BACKGROUND: Recent genome-wide association studies (GWASs) have suggested several susceptibility loci of hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC) by statistical analysis at individual single-nucleotide polymorphisms (SNPs). However, these loci only explain a small fraction of HBV-related HCC heritability. In the present study, we aimed to identify additional susceptibility loci of...
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