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Article

Histone H3K9 methylation promotes formation of genome compartments in Caenorhabditis elegans via chromosome compaction and perinuclear anchoring.

Proceedings of the National Academy of Sciences of the United States of America - 26 May 2020

Bian Qian, Anderson Erika C, Yang Qiming, Meyer Barbara J

Abstract excerpt

Genomic regions preferentially associate with regions of similar transcriptional activity, partitioning genomes into active and inactive compartments within the nucleus. Here we explore mechanisms controlling genome compartment organization in Caenorhabditis elegans and investigate roles for compartments in regulating gene expression. Distal arms of C. elegans chromosomes, which are enriched for heterochromatic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 32385148
DOI: 10.1073/pnas.2002068117
PMCID: PMC7261013

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