Article
Clinicopathologic and Molecular Characteristics of Familial Adenomatous Polyposis-associated Traditional Serrated Adenoma.
The American journal of surgical pathology - 1 Sept 2020
Okamura Takuma, Hashimoto Taiki, Naka Tomoaki, Yoshida Teruhiko, Tanabe Noriko, Ogawa Reiko, Yamada Masayoshi, Saito Yutaka, Yatabe Yasushi, Sekine Shigeki
Abstract excerpt
Colorectal carcinogenesis in familial adenomatous polyposis (FAP) follows a conventional adenoma-carcinoma sequence. However, previous studies have also reported the occurrence of traditional serrated adenomas (TSAs) in patients with FAP. In the present study, we analyzed the clinicopathologic and molecular features of 37 TSAs from 21 FAP patients. Histologically, the majority of FAP-associated TSAs showed...
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