Article
Clinicopathological characteristics of serrated polyps as precursors to colorectal cancer: Current status and management.
Journal of gastroenterology and hepatology - 1 Feb 2017
Okamoto Koichi, Kitamura Shinji, Kimura Tetsuo, Nakagawa Tadahiko, Sogabe Masahiro, Miyamoto Hiroshi, Muguruma Naoki, Takayama Tetsuji
Abstract excerpt
Serrated polyps have long been thought to lack malignant potential in the human colorectum. However, identification of the serrated pathway to colorectal cancer based on molecular biology has improved our understanding of the pathogenesis of colorectal cancers. Accordingly, serrated polyps such as traditional serrated adenoma and sessile serrated adenoma/polyps (SSA/P) are now considered to be precursor lesions...
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