Article

Consideration of genetic and sex effects in mice enhances consilience with human addiction studies

2020-02-15

Abstract excerpt

Concerns about external validity of rodent models and translation of findings across species are often based on narrow investigations of populations with limited diversity. Sources of individual variation – including genetics and sex – are only infrequently encompassed in model organism studies. As with most complex diseases, risk for cocaine use disorder is subject to considerable inter-individual variation. Expl...

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Literature Corpus work: a3315d6e-6cb6-54d0-aebd-923e127dfa86
DOI: 10.1101/2020.02.14.949784

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