Acute sensitivity vs. context-specific sensitization to cocaine as a function of genotype.

doi:10.1016/0091-3057(95)02062-4

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Article

Acute sensitivity vs. context-specific sensitization to cocaine as a function of genotype.

Pharmacology, biochemistry, and behavior - 1 Mar 1996

Elmer G I, Gorelick D A, Goldberg S R, Rothman R B

Abstract excerpt

Individual variability in the acute and chronic effects of psychomotor stimulants is due, in part, to genetic factors. The purpose of this series of studies was to utilize a behavioral model of sensitization, namely increased locomotor activity, to assess individual variability in sensitization to the chronic effects of cocaine and its relationship to the acute stimulant effects of cocaine. Because the degree of...

Topics

Animals
Cocaine
Dose-Response Relationship, Drug
Genotype
Locomotion
Male
Mice
Mice, Inbred C57BL
Time Factors

Source

Open in PubMed

Identifiers

PMID: 8866964
DOI: 10.1016/0091-3057(95)02062-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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