Article
Understanding polygenic models, their development and the potential application of polygenic scores in healthcare.
Journal of medical genetics - 1 Nov 2020
Babb de Villiers Chantal, Kroese Mark, Moorthie Sowmiya
Abstract excerpt
The use of genomic information to better understand and prevent common complex diseases has been an ongoing goal of genetic research. Over the past few years, research in this area has proliferated with several proposed methods of generating polygenic scores. This has been driven by the availability of larger data sets, primarily from genome-wide association studies and concomitant developments in statistical...
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