Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A rapid generalized least squares model for a genome-wide quantitative trait association analysis in families.

Human heredity - 1 Jan 2011

Li Xiang, Basu Saonli, Miller Michael B, Iacono William G, McGue Matt

Abstract excerpt

Genome-wide association studies (GWAS) using family data involve association analyses between hundreds of thousands of markers and a trait for a large number of related individuals. The correlations among relatives bring statistical and computational challenges when performing these large-scale association analyses. Recently, several rapid methods accounting for both within- and between-family variation have been...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Algorithms
Share to Computer Simulation
Share to Genetics, Population

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genome-Wide Association Study

Share to Least-Squares Analysis

Share to Models, Genetic

Share to Polymorphism, Single Nucleotide

Share to Quantitative Trait Loci

Source

Open in PubMed Open full text

Identifiers

PMID: 21474944
DOI: 10.1159/000324839
PMCID: PMC3080778

Genes

GLS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A rapid generalized least squares model for a genome-wide quantitative trait association analysis in families.PMID 21474944Read ↗

Bivariate traits association analysis using generalized estimating equations in family data.Semantic proximity Read ↗

Genomewide rapid association using mixed model and regression: a fast and simple method for genomewide pedigree-based quantitative trait loci association analysis.Semantic proximity Read ↗

A rapid gene-based genome-wide association test with multivariate traits.Semantic proximity Read ↗

GEE-based SNP set association test for continuous and discrete traits in family-based association studies.Semantic proximity Read ↗

A generalized family-based association test for dichotomous traits.Semantic proximity Read ↗

Adjusting family relatedness in data-driven burden test of rare variants.Semantic proximity Read ↗

Bivariate association analyses for the mixture of continuous and binary traits with the use of extended generalized estimating equations.Semantic proximity Read ↗

Bivariate association analysis for quantitative traits using generalized estimation equation.Semantic proximity Read ↗

Sequence robust association test for familial data.Semantic proximity Read ↗

Genome-wide association mapping including phenotypes from relatives without genotypes.Semantic proximity Read ↗

Two-stage association tests for genome-wide association studies based on family data with arbitrary family structure.Semantic proximity Read ↗

A hybrid bayesian approach for genome-wide association studies on related individuals.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.