Article
GEE-based SNP set association test for continuous and discrete traits in family-based association studies.
Genetic epidemiology - 1 Dec 2013
Wang Xuefeng, Lee Seunggeun, Zhu Xiaofeng, Redline Susan, Lin Xihong
Abstract excerpt
Family-based genetic association studies of related individuals provide opportunities to detect genetic variants that complement studies of unrelated individuals. Most statistical methods for family association studies for common variants are single marker based, which test one SNP a time. In this paper, we consider testing the effect of an SNP set, e.g., SNPs in a gene, in family studies, for both continuous and...
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