Article
Landscape of genomic imprinting and its functions in the mouse mammary gland.
Journal of molecular cell biology - 5 May 2020
Xu Haibo, Zhao Lina, Feng Xu, Ma Yujie, Chen Wei, Zou Li, Yang Qin, Sun Jihong, Yu Hong, Jiao Baowei
Abstract excerpt
Genomic imprinting is an epigenetic modification of DNA, whereby gene expression is restricted to either maternally or paternally inherited alleles. Imprinted genes (IGs) in the placenta and embryo are essential for growth regulation and nutrient supply. However, despite being an important nutrition delivery organ, studies on mammary gland genomic imprinting remain limited. In this study, we found that both the...
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