Article
A survey of tissue-specific genomic imprinting in mammals.
Molecular genetics and genomics : MGG - 1 Aug 2012
Prickett Adam R, Oakey Rebecca J
Abstract excerpt
In mammals, most somatic cells contain two copies of each autosomal gene, one inherited from each parent. When a gene is expressed, both parental alleles are usually transcribed. However, a subset of genes is subject to the epigenetic silencing of one of the parental copies by genomic imprinting. In this review, we explore the evidence for variability in genomic imprinting between different tissue and cell types....
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