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Article

The Regulation and Biological Significance of Genomic Imprinting in Mammals

1 Jun 2003

Abstract excerpt

Genomic imprinting is a system of non-Mendelian inheritance that is unique to mammals. Two types of imprinted genes show parent-of-origin-specific expression patterns: the paternally expressed genes (Pegs), and the maternally expressed genes (Megs). Parental genomic imprinting memory is maintained in the somatic cell lineage and regulates the expression of Pegs and Megs, while it is erased and re-established in...

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PMID: 12869525
DOI: 10.1093/jb/mvg090

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