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Article

Functional heterogeneity in senescence.

Biochemical Society transactions - 30 Jun 2020

Kirschner Kristina, Rattanavirotkul Nattaphong, Quince Megan F, Chandra Tamir

Abstract excerpt

Senescence is a tumour suppressor mechanism which is cell-intrinsically activated in the context of cellular stress. Senescence can further be propagated to neighbouring cells, a process called secondary senescence induction. Secondary senescence was initially shown as a paracrine response to the secretion of cytokines from primary senescent cells. More recently, juxtacrine Notch signalling has been implicated in...

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Identifiers

PMID: 32369550
DOI: 10.1042/BST20190109
PMCID: PMC7329341

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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