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Cellular Senescence: Mechanisms and Therapeutic Potential

25 Nov 2021

Abstract excerpt

Cellular senescence is a complex and multistep biological process which cells can undergo in response to different stresses. Referring to a highly stable cell cycle arrest, cellular senescence can influence a multitude of biological processes-both physiologically and pathologically. While phenotypically diverse, characteristics of senescence include the expression of the senescence-associated secretory phenotype,...

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PMID: 34944585
DOI: 10.3390/biomedicines9121769

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