Article
The metabolome as a link in the genotype-phenotype map for peroxide resistance in the fruit fly, Drosophila melanogaster.
BMC genomics - 4 May 2020
Harrison Benjamin R, Wang Lu, Gajda Erika, Hoffman Elise V, Chung Brian Y, Pletcher Scott D, Raftery Daniel, Promislow Daniel E L
Abstract excerpt
BACKGROUND: Genetic association studies that seek to explain the inheritance of complex traits typically fail to explain a majority of the heritability of the trait under study. Thus, we are left with a gap in the map from genotype to phenotype. Several approaches have been used to fill this gap, including those that attempt to map endophenotype such as the transcriptome, proteome or metabolome, that underlie...
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