Article
Salivary cortisol response to psychosocial stress in the late evening depends on CRHR1 genotype.
Psychoneuroendocrinology - 1 Jun 2020
Weeger J, Ising M, Müller-Myhsok B, Uhr M, Schmidt U, Steiger A
Abstract excerpt
The activation of the hypothalamus-pituitary-adrenal (HPA) axis is induced by stress. Imbalances in this system increase the risk of developing stress related disorders including mental illness. Variants in the single nucleotide polymorphism (SNP) rs110402 of the corticotropin-releasing hormone receptor type I (CRHR1) gene have been shown in interaction with childhood maltreatment to increase the vulnerability to...
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