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Article

Evaluation of the expression levels of BRAFV600E mRNA in primary tumors of thyroid cancer using an ultrasensitive mutation assay.

BMC cancer - 1 May 2020

Tran Tien Viet, Dang Kien Xuan, Pham Quynh Huong, Nguyen Ung Dinh, Trinh Nhung Thi Trang, Hoang Luong Van, Ho Son Anh, Nguyen Ba Van, Nguyen Duc Trong, Trinh Dung Tuan, Tran Dung Ngoc, Orpana Arto, Stenman Ulf-Håkan, Stenman Jakob, Ho Tho Huu

Abstract excerpt

BACKGROUND: The BRAFV600E gene encodes for the mutant BRAFV600E protein, which triggers downstream oncogenic signaling in thyroid cancer. Since most currently available methods have focused on detecting BRAFV600E mutations in tumor DNA, there is limited information about the level of BRAFV600E mRNA in primary tumors of thyroid cancer, and the diagnostic relevance of these RNA mutations is not known. METHODS:...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 32357861
DOI: 10.1186/s12885-020-06862-w
PMCID: PMC7195771

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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