Article
Evaluation of molecular diagnostic approaches for the detection of BRAF p.V600E mutations in papillary thyroid cancer: Clinical implications.
PloS one - 1 Jan 2017
Kowalik Artur, Kowalska Aldona, Walczyk Agnieszka, Chodurska Renata, Kopczyński Janusz, Chrapek Magdalena, Wypiórkiewicz Elżbieta, Chłopek Małgorzata, Pięciak Liliana, Gąsior-Perczak Danuta, Pałyga Iwona, Gruszczyński Krzysztof, Nowak Ewelina, Góźdź Stanisław
Abstract excerpt
Differentiated papillary thyroid cancer (PTC) is the most common cancer of the endocrine system. PTC has a very good prognosis and a high 5 year survival rate; however, some patients are unresponsive to treatment, and their diagnosis eventually results in death. Recent efforts have focused on searching for prognostic and predictive factors that may enable treatment personalization and monitoring across the course...
Topics
- Adult
- Aged
- Alleles
- Base Sequence
- Carcinoma
- Carcinoma, Papillary
- DNA
- Female
- Genotype
- Humans