Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Application of BRAF, NRAS, KRAS mutations as markers for the detection of papillary thyroid cancer from FNAB specimens by pyrosequencing analysis.

Clinical chemistry and laboratory medicine - 1 Aug 2013

Park Seo-Jin, Sun Je Young Hannah, Hong Kyungran, Kwak Jin Young, Kim Eun-Kyung, Chung Woung Youn, Choi Jong Rak

Abstract excerpt

BACKGROUND: BRAFV600E, the most common BRAF gene mutation, is detected in approximately 50% of sporadic papillary thyroid carcinoma (PTC) and may be associated with triggering tumorigenesis of PTC. The aim of our study was to discover additional mutations to increase the diagnostic performance of molecular tests in screening for thyroid cancer from fine needle aspiration biopsy (FNAB) specimens. METHODS: DNA was...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biopsy, Fine-Needle
Share to Carcinoma

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Carcinoma, Papillary

Share to GTP Phosphohydrolases

Share to Proto-Oncogene Proteins p21(ras)

Share to ras Proteins

Share to Thyroid Cancer, Papillary

Share to Thyroid Neoplasms

Source

Identifiers

PMID: 23585181
DOI: 10.1515/cclm-2012-0375

Genes

BRAF
NRAS
KRAS

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Application of BRAF, NRAS, KRAS mutations as markers for the detection of papillary thyroid cancer from FNAB specimens by pyrosequencing analysis.PMID 23585181Read ↗

Pyrosequencing cut-off value identifying BRAFV600E mutation in fine needle aspiration samples of thyroid nodules.Semantic proximity Read ↗

Detection of RAS mutation by pyrosequencing in thyroid cytology samples.Semantic proximity Read ↗

Comparison Between Real-Time PCR and Pyrosequencing for Detection of BRAF V600E Mutation in Thyroid Fine-Needle Aspirates.Semantic proximity Read ↗

Detection of BRAF Mutation on Fine Needle Aspiration Biopsy Specimens: A New Diagnostic Tool for Papillary Thyroid CancerSemantic proximity Read ↗

Diagnostic value of pyrosequencing for the BRAF V600E mutation in ultrasound-guided fine-needle aspiration biopsy samples of thyroid incidentalomas.Semantic proximity Read ↗

A testing algorithm for detection of the B-type Raf kinase V600E mutation in papillary thyroid carcinoma.Semantic proximity Read ↗

Detection of BRAF V600E mutation with thyroid tissue using pyrosequencing: comparison with PNA-clamping and real-time PCR.Semantic proximity Read ↗

Diagnostic utility of BRAFV600E mutation testing in thyroid nodules in elderly patients.Semantic proximity Read ↗

Detection of papillary thyroid carcinoma by analysis of BRAF and RET/PTC1 mutations in fine-needle aspiration biopsies of thyroid nodules.Semantic proximity Read ↗

Detection of BRAF mutations in thyroid nodules by allele-specific PCR using a dual priming oligonucleotide system.Semantic proximity Read ↗

Assessment of molecular testing in fine-needle aspiration biopsy samples: an experience in a Chinese population.Semantic proximity Read ↗

The usefulness of a novel fully automated PCR-based Idylla test for detection of the BRAF V600E mutation in thyroid tissue: comparison with PNA-clamping PCR, real-time PCR and pyrosequencingSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.