Article
Shifted termination assay (STA) fragment analysis to detect BRAF V600 mutations in papillary thyroid carcinomas.
Diagnostic pathology - 24 Jul 2013
Kang So Young, Ahn Soomin, Lee Sun-Mi, Jeong Ji Yun, Sung Ji-Youn, Oh Young Lyun, Kim Kyoung-Mee
Abstract excerpt
BACKGROUND: BRAF mutation is an important diagnostic and prognostic marker in patients with papillary thyroid carcinoma (PTC). To be applicable in clinical laboratories with limited equipment, diverse testing methods are required to detect BRAF mutation. METHODS: A shifted termination assay (STA) fragment analysis was used to detect common V600 BRAF mutations in 159 PTCs with DNAs extracted from formalin-fixed...
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