Article
The Association of the BRAF-V600E Mutation with the Expression of the Molecular Markers in the Primary Tumor and Metastatic Tissue in Papillary Thyroid Cancer.
Asian Pacific journal of cancer prevention : APJCP - 1 Jul 2021
Spirina Liudmila V, Chizhevskaya Svetlana Yu, Kovaleva Irina V, Kondakova Irina V
Abstract excerpt
OBJECTIVE: The aim of this study was investigation the AKT / mTOR signaling pathway components, transcriptional and growth factors, as well as steroid hormone receptors and nuclear factors Brn-3α and TRIM16 expression in the tissue of the primary thyroid tumor and metastases, depending on the BRAF- V600E status. MATERIAL AND METHODS: The study was enrolled 20 patients with PTCs, who underwent surgical treatment....
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