Diagnostic Value of Immunohistochemistry for the Detection of the <i> BRAF ^V600E </i> Mutation in Papillary Thyroid Carcinoma: Comparative Analysis with Three DNA-Based Assays

Abstract excerpt

BACKGROUND: The aim of this study was to compare the detection of BRAF(V600E) by immunohistochemistry (IHC) using a mutation-specific antibody with molecular biology methods for evaluation of papillary thyroid carcinoma (PTC) patients. PATIENTS AND METHODS: This study concerned 198 consecutive conventional PTC patients, of which the majority were women (133/198; 67%), with a mean age of 56 years (range 19-79...

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