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Article

Val66Met BDNF polymorphism as a vulnerability factor for inflammation-associated depressive symptoms in women with breast cancer.

Journal of affective disorders - 1 Jun 2016

Dooley Larissa N, Ganz Patricia A, Cole Steve W, Crespi Catherine M, Bower Julienne E

Abstract excerpt

BACKGROUND: Inflammation contributes to the development of depression in a subset of individuals, but risk factors that render certain individuals particularly vulnerable to inflammation-associated depression are undetermined. Drawing from animal studies showing that reduced neuroplasticity mediates effects of inflammation on depression, we hypothesized that individuals genetically predisposed to lower levels of...

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Source

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Identifiers

PMID: 26967918
DOI: 10.1016/j.jad.2016.02.059
PMCID: PMC4836957

Genes

BDNF
CRP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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